diff --git a/src/dstack/_internal/cli/commands/server.py b/src/dstack/_internal/cli/commands/server.py
index 255f92e9a5..3769d9b77d 100644
--- a/src/dstack/_internal/cli/commands/server.py
+++ b/src/dstack/_internal/cli/commands/server.py
@@ -103,6 +103,8 @@ def _command(self, args: argparse.Namespace):
             reload_excludes=reload_excludes,
             log_level=uvicorn_log_level,
             workers=1,
+            # uvloop spawns subprocesses with fork(), which can hang the server (#4362).
+            loop="asyncio",
         )
 
     def _configure_logging(self) -> None:
diff --git a/src/tests/_internal/cli/commands/test_server.py b/src/tests/_internal/cli/commands/test_server.py
new file mode 100644
index 0000000000..5b8b4d0e9c
--- /dev/null
+++ b/src/tests/_internal/cli/commands/test_server.py
@@ -0,0 +1,12 @@
+import os
+from unittest.mock import patch
+
+from dstack._internal.cli.commands import server
+from tests._internal.cli.common import run_dstack_cli
+
+
+class TestServerCommand:
+    def test_runs_uvicorn_on_asyncio_loop(self):
+        with patch.dict(os.environ), patch.object(server.uvicorn, "run") as uvicorn_run:
+            assert run_dstack_cli(["server"]) == 0
+        assert uvicorn_run.call_args.kwargs["loop"] == "asyncio"