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@WayScience

The Way Lab

The Way Lab at CU Anschutz

Welcome to the open-source GitHub organization hosted by The Way Lab.

We are a team of scientists and engineers developing methods and software for analyzing microscopy images of cells. Our mission is to reduce human suffering.

Our website contains complete details of our research projects, team members, and funding: https://www.waysciencelab.com/

Check out a few of our open-source projects!

Select Software

Select Projects

We are leading multidisciplinary scientists in a variety of team-science initiatives.

Pediatric Cancer Cell Morphology Atlas

We are developing a reference Cell Painting data set of pediatric cancer cell lines, and performing several high-throughput, high-content phenotypic drug screens.

3D profiling of Neurofibromatosis Type 1 patient-derived organoids

We are developing a 3D image analysis pipeline to profile patient-derived organoids from neurofibromatosis type 1 (NF1) patients, and we will be performing several high-throughput, high-content phenotypic drug screens.

Finding new therapeutics for cardiac fibrosis

We are identifying fundamental differences between cardiac fibroblasts from patients with and without heart failure, and we are developing a high-throughput, high-content phenotypic drug screen to identify new therapeutics for cardiac fibrosis.

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  1. pccma pccma Public

    Pediatric Cancer Cell Morphology Atlas

    Jupyter Notebook 2

  2. ZedProfiler ZedProfiler Public

    Featurizing high-content 3D microscopy images

    Python 2 3

  3. buscar buscar Public

    Single cell hit calling for high-content screens

    Python 9 3

  4. ome-arrow ome-arrow Public

    Using OME specifications with Apache Arrow for fast, queryable, and language agnostic bioimage data.

    Python 8 1

  5. iceberg-bioimage iceberg-bioimage Public

    A format-agnostic framework for cataloging and querying bioimaging data (Parquet, OME-Zarr, OME-TIFF) with Apache Iceberg

    Python 3 2

  6. nf1_schwann_cell_painting_data nf1_schwann_cell_painting_data Public

    This repository contains all the modules to perform image-based analysis with CellProfiler on NF1 Schwann cell data.

    Jupyter Notebook 8 6

Repositories

Showing 10 of 108 repositories
  • ome-arrow Public

    Using OME specifications with Apache Arrow for fast, queryable, and language agnostic bioimage data.

    WayScience/ome-arrow's past year of commit activity
    Python 8 BSD-3-Clause 1 7 3 Updated Oct 20, 2026
  • NF1_organoid_profile_analysis Public

    This repo contains analysis code of profiles generated in multiple image-based profiling repos.

    WayScience/NF1_organoid_profile_analysis's past year of commit activity
    Jupyter Notebook 1 BSD-3-Clause 3 5 4 Updated Oct 19, 2026
  • buscar Public

    Single cell hit calling for high-content screens

    WayScience/buscar's past year of commit activity
    Python 9 BSD-3-Clause 3 8 0 Updated Oct 19, 2026
  • formascute Public

    🐢 Exploring the structure of software workflow execution through small, reproducible experiments.

    WayScience/formascute's past year of commit activity
    Shell 0 BSD-3-Clause 1 0 1 Updated Oct 16, 2026
  • virtual_stain_flow Public

    For developing virtual staining models

    WayScience/virtual_stain_flow's past year of commit activity
    Python 2 BSD-3-Clause 1 7 1 Updated Oct 15, 2026
  • pedcp90 Public

    Image analysis and image-based profiling for pedcp90 dataset (PCCMA pilot)

    WayScience/pedcp90's past year of commit activity
    Jupyter Notebook 7 CC0-1.0 5 6 1 Updated Oct 14, 2026
  • waysciencelab.com Public

    Homepage for all happenings in the Way Lab at CU Anschutz

    WayScience/waysciencelab.com's past year of commit activity
    SCSS 4 BSD-3-Clause 11 2 0 Updated Oct 14, 2026
  • cardiac_fibrosis_rescue_screen_profiling Public

    Image analysis and image-based profiling of a fibrosis drug screen to identify compound hits using a machine learning model.

    WayScience/cardiac_fibrosis_rescue_screen_profiling's past year of commit activity
    Jupyter Notebook 3 CC0-1.0 5 14 0 Updated Oct 13, 2026
  • pccma Public

    Pediatric Cancer Cell Morphology Atlas

    WayScience/pccma's past year of commit activity
    Jupyter Notebook 0 BSD-3-Clause 2 0 0 Updated Oct 13, 2026
  • PRISM_Agent_LITL_experiments Public

    Exploring how to better utilize Lab In The Loop (LITL) data in agentic systems with DSPy. Built with DSPy, this repo provides modular agent tools and academic experiments on PRISM-inspired drug repurposing data to test agentic system improvement under different toolsets.

    WayScience/PRISM_Agent_LITL_experiments's past year of commit activity
    Python 1 BSD-3-Clause 1 0 0 Updated Oct 12, 2026

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